{"id":16017,"date":"2025-06-03T15:30:09","date_gmt":"2025-06-03T13:30:09","guid":{"rendered":"https:\/\/www.avantea.it\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/"},"modified":"2025-08-05T09:56:47","modified_gmt":"2025-08-05T07:56:47","slug":"opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding","status":"publish","type":"post","link":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/","title":{"rendered":"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"16017\" class=\"elementor elementor-16017 elementor-15380\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9f7a842 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"9f7a842\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6505861\" data-id=\"6505861\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c8deb46 elementor-widget elementor-widget-text-editor\" data-id=\"c8deb46\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>A new generation of sport horses is emerging, and they all have something in common: they were born thanks to the OPU-ICSI technique. This is no longer a scientific curiosity or an extreme solution, but an increasingly widespread reality in competition arenas, auction catalogs, and the strategic plans of top breeders. And behind this evolution is a name that has played a decisive role in making it possible: <strong>Avantea<\/strong>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t<div class=\"elementor-element elementor-element-c8d188d e-con-full e-flex e-con e-parent\" data-id=\"c8d188d\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-8027c64 e-con-full e-flex e-con e-child\" data-id=\"8027c64\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-138012b e-con-full e-flex e-con e-child\" data-id=\"138012b\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b34ade4 title3 bold elementor-widget elementor-widget-heading\" data-id=\"b34ade4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Why OPU-ICSI Is Transforming Breeding<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4679d3c elementor-widget elementor-widget-text-editor\" data-id=\"4679d3c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Initially developed as a solution for complex cases\u2014mares in sport, mares with fertility issues, or the use of rare semen\u2014OPU-ICSI is now becoming a standard choice, even in routine breeding, to maximize both the production and genetic value of foals.<\/p><p><br \/>Thanks to this technology, it is possible to plan targeted matings between the best mares and top stallions, including those who passed away years ago\u2014like Chacco-Blue, Cumano, Heartbreaker, and Carthago Z\u2014whose offspring continue to succeed internationally. The sporting results confirm that OPU-ICSI is not just a technical solution, but a true tool for advanced genetic selection.<\/p><figure class=\"wp-block-gallery has-nested-images columns-2 is-cropped wp-block-gallery-2 is-layout-flex wp-block-gallery-is-layout-flex\"><\/figure>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d7cb004 e-con-full e-flex e-con e-child\" data-id=\"d7cb004\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1cc766e e-con-full e-flex e-con e-parent\" data-id=\"1cc766e\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-23184d0 e-con-full e-flex e-con e-child\" data-id=\"23184d0\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-462596f e-con-full e-flex e-con e-child\" data-id=\"462596f\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-44e7464 e-con-full e-flex e-con e-child\" data-id=\"44e7464\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-619984c title3 bold elementor-widget elementor-widget-heading\" data-id=\"619984c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">The Numbers Speak for Themselves: More ICSI Horses, More Competitive<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-213a520 elementor-widget elementor-widget-text-editor\" data-id=\"213a520\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>A study conducted by<a href=\"https:\/\/www.hippomundo.com\/en\/news\/old-blood-new-champions-the-rise-of-icsi-bred-sport-horses-from-late-stallions\" target=\"_blank\" rel=\"noopener\"><span style=\"text-decoration: underline;\"><strong> Hippomundo<\/strong><\/span><\/a> highlighted the real boom in foals born through ICSI, especially from stallions no longer available.<\/p><p>Beyond the numbers, the sporting quality of these horses is striking: 66.8% of Chacco-Blue\u2019s offspring born in recent years are active in international sport, with a \u201cBlack Type\u201d (notable sports results) rate of over 68% for horses aged eight and up. Young talents like <strong>Celeana Des Joanins Z<\/strong>, <strong>Champione Blue Z<\/strong>, and <strong>Rotterdam De Muze<\/strong> are concrete examples of how ICSI doesn\u2019t just preserve genetics\u2014it turns them into results.<\/p><figure class=\"wp-block-gallery has-nested-images columns-2 is-cropped wp-block-gallery-2 is-layout-flex wp-block-gallery-is-layout-flex\"><\/figure>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-62e9994 e-con-full e-flex e-con e-parent\" data-id=\"62e9994\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-3f9e2bb e-con-full e-flex e-con e-child\" data-id=\"3f9e2bb\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-24c816f e-con-full e-flex e-con e-child\" data-id=\"24c816f\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9212ad1 title3 bold elementor-widget elementor-widget-heading\" data-id=\"9212ad1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">The Italian Case: OPU-ICSI in the 2025 FISE Young Horses Circuit Sponsored by Avantea<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-906a884 elementor-widget elementor-widget-text-editor\" data-id=\"906a884\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>In Italy too, the phenomenon is rapidly growing. Data collected during the first two events of the <strong>2025 FISE Young Horses Circuit sponsored by Avantea<\/strong> clearly demonstrate this.<br \/>The young horse categories saw a significant presence of horses born via this innovative technique.<\/p><p>\u00a0<\/p><p>These numbers show how ICSI is gaining ground in the emerging generations of sport horses\u2014a choice that ensures superior genetics and strong competitive potential.<\/p><figure class=\"wp-block-gallery has-nested-images columns-2 is-cropped wp-block-gallery-2 is-layout-flex wp-block-gallery-is-layout-flex\"><\/figure>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d38751a e-con-full e-flex e-con e-child\" data-id=\"d38751a\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3fd1236 e-con-full e-flex e-con e-parent\" data-id=\"3fd1236\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-b578bba e-con-full e-flex e-con e-child\" data-id=\"b578bba\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-7e5d7be e-con-full e-flex e-con e-child\" data-id=\"7e5d7be\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0acfb38 e-con-full e-flex e-con e-child\" data-id=\"0acfb38\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6a337c3 elementor-widget elementor-widget-text-editor\" data-id=\"6a337c3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The effectiveness of ICSI was further proven by competition results:<\/p><p><strong>Vincenzo Chimirri<\/strong> placed second in Bedizzole in the 5-year-old FISE precision h120 class, while <strong>Lorenzo Correddu<\/strong> won the same category in Cattolica. Also in Cattolica, <strong>Alessandro Colombo<\/strong> triumphed in the 4-year-old FISE precision h105 class\u2014demonstrating the high competitive level of ICSI-born horses.<\/p><p><br \/>These successes prove that horses produced with this technology can compete at the highest level, equal to those born using traditional breeding methods.<\/p><figure class=\"wp-block-gallery has-nested-images columns-2 is-cropped wp-block-gallery-2 is-layout-flex wp-block-gallery-is-layout-flex\"><\/figure>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-58ff343 e-con-full e-flex e-con e-parent\" data-id=\"58ff343\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-fd26e11 e-con-full e-flex e-con e-child\" data-id=\"fd26e11\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-d26f20e e-con-full e-flex e-con e-child\" data-id=\"d26f20e\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e4761f9 title3 bold elementor-widget elementor-widget-heading\" data-id=\"e4761f9\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Even the mothers of champions are selected for OPU-ICSI programs<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-08161a7 elementor-widget elementor-widget-text-editor\" data-id=\"08161a7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Even if many horses currently competing weren\u2019t born via OPU-ICSI, their dams have recently begun oocyte collection programs using this technique at Avantea\u2014further proof of a growing trend among top breeders to adopt advanced reproductive biotechnologies to pass on elite bloodlines to future generations.<\/p><figure class=\"wp-block-gallery has-nested-images columns-2 is-cropped wp-block-gallery-2 is-layout-flex wp-block-gallery-is-layout-flex\"><\/figure>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4f91b14 title3 bold elementor-widget elementor-widget-heading\" data-id=\"4f91b14\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Not Just Sport Success: ICSI Foals Are Leading the Auctions<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0a35f89 elementor-widget elementor-widget-text-editor\" data-id=\"0a35f89\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The commercial value of OPU-ICSI foals continues to rise, confirming the market\u2019s growing interest in this technique. A particularly significant figure comes from the <strong>Zangersheide Quality Auction<\/strong>, one of the most prestigious in Europe: in 2024, foals conceived via OPU-ICSI fetched an average price of over <strong>\u20ac50,000<\/strong>, more than <strong>20% higher<\/strong> than those born through traditional methods such as artificial insemination or flushing.<\/p><p>\u00a0<\/p><p>This gap is no coincidence\u2014it clearly reflects the market\u2019s recognition of the genetic value, targeted selection, and sporting potential of in vitro-born horses.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ba7de5f title3 bold elementor-widget elementor-widget-heading\" data-id=\"ba7de5f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">A Technique for the Future\u2014But Already a Present Reality<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d45adcc elementor-widget elementor-widget-text-editor\" data-id=\"d45adcc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>OPU-ICSI is emerging as one of the most strategic and transformative innovations in modern sport horse breeding. The figures, results, and decisions of top breeders show that this isn\u2019t just cutting-edge technology\u2014it\u2019s a real, practical tool to produce more competitive, more valuable horses with greater genetic potential.<\/p><p>\u00a0<\/p><p>Whether it\u2019s about performance in competition, auction success, or reproductive planning, ICSI has already changed how breeding is perceived and practiced.<\/p><p><strong>The future of equine genetics has already begun\u2014 and it\u2019s in vitro.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2035469 e-con-full e-flex e-con e-child\" data-id=\"2035469\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-672b8e0 e-con-full e-flex e-con e-parent\" data-id=\"672b8e0\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Avantea is proud to announce the publication in the prestigious journal Science Advances of the study titled \u201cRetinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models\u201d (Ferla et al., 2025), the result of a collaboration with TIGEM, AAVantgarde Bio, and other research institutions.<\/p>\n","protected":false},"author":1,"featured_media":15384,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[113],"tags":[154],"class_list":["post-16017","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nicht-kategorisiert","tag-news-de"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.4 - aioseo.com -->\n\t<meta name=\"description\" content=\"Avantea is proud to announce the publication in the prestigious journal Science Advances of the study titled \u201cRetinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models\u201d (Ferla et al., 2025), the result of a collaboration with TIGEM, AAVantgarde Bio, and other research institutions.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"maverg\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.avantea.it\/en\/news-en\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/\" \/>\n\t\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 5.0.4\" \/>\n\t\t<meta property=\"og:locale\" content=\"de_DE\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Avantea | Assisted equine reproduction -\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding - Avantea | Assisted equine reproduction\" \/>\n\t\t<meta property=\"og:description\" content=\"Avantea is proud to announce the publication in the prestigious journal Science Advances of the study titled \u201cRetinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models\u201d (Ferla et al., 2025), the result of a collaboration with TIGEM, AAVantgarde Bio, and other research institutions.\" \/>\n\t\t<meta property=\"og:url\" content=\"https:\/\/www.avantea.it\/en\/news-en\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/\" \/>\n\t\t<meta property=\"article:published_time\" content=\"2025-06-03T13:30:09+00:00\" \/>\n\t\t<meta property=\"article:modified_time\" content=\"2025-08-05T07:56:47+00:00\" \/>\n\t\t<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n\t\t<meta name=\"twitter:title\" content=\"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding - Avantea | Assisted equine reproduction\" \/>\n\t\t<meta name=\"twitter:description\" content=\"Avantea is proud to announce the publication in the prestigious journal Science Advances of the study titled \u201cRetinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models\u201d (Ferla et al., 2025), the result of a collaboration with TIGEM, AAVantgarde Bio, and other research institutions.\" \/>\n\t\t<script type=\"application\/ld+json\" class=\"aioseo-schema\">\n\t\t\t{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"BlogPosting\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#blogposting\",\"name\":\"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding - Avantea | Assisted equine reproduction\",\"headline\":\"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding\",\"author\":{\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/author\\\/maverg\\\/#author\"},\"publisher\":{\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/#organization\"},\"image\":{\"@type\":\"ImageObject\",\"url\":\"https:\\\/\\\/www.avantea.it\\\/wp-content\\\/uploads\\\/2025\\\/05\\\/BLU-HORSE_S5_2331-2048x1365-1.jpg\",\"width\":1474,\"height\":982},\"datePublished\":\"2025-06-03T15:30:09+02:00\",\"dateModified\":\"2025-08-05T09:56:47+02:00\",\"inLanguage\":\"de-DE\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#webpage\"},\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#webpage\"},\"articleSection\":\"Nicht kategorisiert, News, Opzionale\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#breadcrumblist\",\"itemListElement\":[{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/#listItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/category\\\/nicht-kategorisiert\\\/#listItem\",\"name\":\"Nicht kategorisiert\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/category\\\/nicht-kategorisiert\\\/#listItem\",\"position\":2,\"name\":\"Nicht kategorisiert\",\"item\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/category\\\/nicht-kategorisiert\\\/\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#listItem\",\"name\":\"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding\"},\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/#listItem\",\"name\":\"Home\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#listItem\",\"position\":3,\"name\":\"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding\",\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/category\\\/nicht-kategorisiert\\\/#listItem\",\"name\":\"Nicht kategorisiert\"}}]},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/#organization\",\"name\":\"Avantea | Assisted equine reproduction\",\"description\":\"Assisted animal reproduction and biotechnological research\",\"url\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"url\":\"https:\\\/\\\/www.avantea.it\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Avantea_Avatar_Youtube.png\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#organizationLogo\",\"width\":558,\"height\":558,\"caption\":\"Logo Avantea\"},\"image\":{\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#organizationLogo\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/author\\\/maverg\\\/#author\",\"url\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/author\\\/maverg\\\/\",\"name\":\"maverg\",\"image\":{\"@type\":\"ImageObject\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#authorImage\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c830d660e2e853637dd6d22b3ef2e69e5716f4d5c15d40e24a3b016e7a9f20cc?s=96&d=mm&r=g\",\"width\":96,\"height\":96,\"caption\":\"maverg\"}},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#webpage\",\"url\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/\",\"name\":\"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding - Avantea | Assisted equine reproduction\",\"description\":\"Avantea is proud to announce the publication in the prestigious journal Science Advances of the study titled \\u201cRetinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models\\u201d (Ferla et al., 2025), the result of a collaboration with TIGEM, AAVantgarde Bio, and other research institutions.\",\"inLanguage\":\"de-DE\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/#website\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#breadcrumblist\"},\"author\":{\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/author\\\/maverg\\\/#author\"},\"creator\":{\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/author\\\/maverg\\\/#author\"},\"image\":{\"@type\":\"ImageObject\",\"url\":\"https:\\\/\\\/www.avantea.it\\\/wp-content\\\/uploads\\\/2025\\\/05\\\/BLU-HORSE_S5_2331-2048x1365-1.jpg\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#mainImage\",\"width\":1474,\"height\":982},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/nicht-kategorisiert\\\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\\\/#mainImage\"},\"datePublished\":\"2025-06-03T15:30:09+02:00\",\"dateModified\":\"2025-08-05T09:56:47+02:00\"},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/#website\",\"url\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/\",\"name\":\"Avantea | Assisted equine reproduction\",\"alternateName\":\"Avantea\",\"inLanguage\":\"de-DE\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.avantea.it\\\/de\\\/#organization\"}}]}\n\t\t<\/script>\n\t\t<!-- All in One SEO -->\n\n","aioseo_head_json":{"title":"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding - Avantea | Assisted equine reproduction","description":"Avantea is proud to announce the publication in the prestigious journal Science Advances of the study titled \u201cRetinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models\u201d (Ferla et al., 2025), the result of a collaboration with TIGEM, AAVantgarde Bio, and other research institutions.","canonical_url":"https:\/\/www.avantea.it\/en\/news-en\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/","robots":"max-image-preview:large","keywords":"","webmasterTools":{"miscellaneous":""},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"BlogPosting","@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#blogposting","name":"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding - Avantea | Assisted equine reproduction","headline":"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding","author":{"@id":"https:\/\/www.avantea.it\/de\/author\/maverg\/#author"},"publisher":{"@id":"https:\/\/www.avantea.it\/de\/#organization"},"image":{"@type":"ImageObject","url":"https:\/\/www.avantea.it\/wp-content\/uploads\/2025\/05\/BLU-HORSE_S5_2331-2048x1365-1.jpg","width":1474,"height":982},"datePublished":"2025-06-03T15:30:09+02:00","dateModified":"2025-08-05T09:56:47+02:00","inLanguage":"de-DE","mainEntityOfPage":{"@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#webpage"},"isPartOf":{"@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#webpage"},"articleSection":"Nicht kategorisiert, News, Opzionale"},{"@type":"BreadcrumbList","@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#breadcrumblist","itemListElement":[{"@type":"ListItem","@id":"https:\/\/www.avantea.it\/de\/#listItem","position":1,"name":"Home","item":"https:\/\/www.avantea.it\/de\/","nextItem":{"@type":"ListItem","@id":"https:\/\/www.avantea.it\/de\/category\/nicht-kategorisiert\/#listItem","name":"Nicht kategorisiert"}},{"@type":"ListItem","@id":"https:\/\/www.avantea.it\/de\/category\/nicht-kategorisiert\/#listItem","position":2,"name":"Nicht kategorisiert","item":"https:\/\/www.avantea.it\/de\/category\/nicht-kategorisiert\/","nextItem":{"@type":"ListItem","@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#listItem","name":"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding"},"previousItem":{"@type":"ListItem","@id":"https:\/\/www.avantea.it\/de\/#listItem","name":"Home"}},{"@type":"ListItem","@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#listItem","position":3,"name":"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding","previousItem":{"@type":"ListItem","@id":"https:\/\/www.avantea.it\/de\/category\/nicht-kategorisiert\/#listItem","name":"Nicht kategorisiert"}}]},{"@type":"Organization","@id":"https:\/\/www.avantea.it\/de\/#organization","name":"Avantea | Assisted equine reproduction","description":"Assisted animal reproduction and biotechnological research","url":"https:\/\/www.avantea.it\/de\/","logo":{"@type":"ImageObject","url":"https:\/\/www.avantea.it\/wp-content\/uploads\/2025\/11\/Avantea_Avatar_Youtube.png","@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#organizationLogo","width":558,"height":558,"caption":"Logo Avantea"},"image":{"@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#organizationLogo"}},{"@type":"Person","@id":"https:\/\/www.avantea.it\/de\/author\/maverg\/#author","url":"https:\/\/www.avantea.it\/de\/author\/maverg\/","name":"maverg","image":{"@type":"ImageObject","@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#authorImage","url":"https:\/\/secure.gravatar.com\/avatar\/c830d660e2e853637dd6d22b3ef2e69e5716f4d5c15d40e24a3b016e7a9f20cc?s=96&d=mm&r=g","width":96,"height":96,"caption":"maverg"}},{"@type":"WebPage","@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#webpage","url":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/","name":"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding - Avantea | Assisted equine reproduction","description":"Avantea is proud to announce the publication in the prestigious journal Science Advances of the study titled \u201cRetinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models\u201d (Ferla et al., 2025), the result of a collaboration with TIGEM, AAVantgarde Bio, and other research institutions.","inLanguage":"de-DE","isPartOf":{"@id":"https:\/\/www.avantea.it\/de\/#website"},"breadcrumb":{"@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#breadcrumblist"},"author":{"@id":"https:\/\/www.avantea.it\/de\/author\/maverg\/#author"},"creator":{"@id":"https:\/\/www.avantea.it\/de\/author\/maverg\/#author"},"image":{"@type":"ImageObject","url":"https:\/\/www.avantea.it\/wp-content\/uploads\/2025\/05\/BLU-HORSE_S5_2331-2048x1365-1.jpg","@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#mainImage","width":1474,"height":982},"primaryImageOfPage":{"@id":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/#mainImage"},"datePublished":"2025-06-03T15:30:09+02:00","dateModified":"2025-08-05T09:56:47+02:00"},{"@type":"WebSite","@id":"https:\/\/www.avantea.it\/de\/#website","url":"https:\/\/www.avantea.it\/de\/","name":"Avantea | Assisted equine reproduction","alternateName":"Avantea","inLanguage":"de-DE","publisher":{"@id":"https:\/\/www.avantea.it\/de\/#organization"}}]},"og:locale":"de_DE","og:site_name":"Avantea | Assisted equine reproduction -","og:type":"article","og:title":"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding - Avantea | Assisted equine reproduction","og:description":"Avantea is proud to announce the publication in the prestigious journal Science Advances of the study titled \u201cRetinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models\u201d (Ferla et al., 2025), the result of a collaboration with TIGEM, AAVantgarde Bio, and other research institutions.","og:url":"https:\/\/www.avantea.it\/en\/news-en\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/","article:published_time":"2025-06-03T13:30:09+00:00","article:modified_time":"2025-08-05T07:56:47+00:00","twitter:card":"summary_large_image","twitter:title":"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding - Avantea | Assisted equine reproduction","twitter:description":"Avantea is proud to announce the publication in the prestigious journal Science Advances of the study titled \u201cRetinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models\u201d (Ferla et al., 2025), the result of a collaboration with TIGEM, AAVantgarde Bio, and other research institutions."},"aioseo_meta_data":{"post_id":"16017","title":null,"description":null,"keywords":null,"keyphrases":{"focus":{"keyphrase":"","score":0,"analysis":{"keyphraseInTitle":{"score":0,"maxScore":9,"error":1}}},"additional":[]},"primary_term":null,"canonical_url":"https:\/\/www.avantea.it\/en\/news-en\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/","og_title":null,"og_description":null,"og_object_type":"default","og_image_type":"default","og_image_url":null,"og_image_width":null,"og_image_height":null,"og_image_custom_url":null,"og_image_custom_fields":null,"og_video":"","og_custom_url":null,"og_article_section":null,"og_article_tags":null,"twitter_use_og":false,"twitter_card":"default","twitter_image_type":"default","twitter_image_url":null,"twitter_image_custom_url":null,"twitter_image_custom_fields":null,"twitter_title":null,"twitter_description":null,"schema":{"blockGraphs":[],"customGraphs":[],"default":{"data":{"Article":[],"Course":[],"Dataset":[],"FAQPage":[],"Movie":[],"Person":[],"Product":[],"ProductReview":[],"Car":[],"Recipe":[],"Service":[],"SoftwareApplication":[],"WebPage":[]},"graphName":"BlogPosting","isEnabled":true},"graphs":[]},"schema_type":"default","schema_type_options":null,"pillar_content":false,"robots_default":true,"robots_noindex":false,"robots_noarchive":false,"robots_nosnippet":false,"robots_nofollow":false,"robots_noimageindex":false,"robots_noodp":false,"robots_notranslate":false,"robots_max_snippet":"-1","robots_max_videopreview":"-1","robots_max_imagepreview":"large","priority":null,"frequency":"default","local_seo":null,"limit_modified_date":false,"created":"2025-06-25 14:32:02","updated":"2026-10-23 08:27:09","focus_keyword":null,"additional_keywords":null,"truseo_locale":null,"ai":null,"breadcrumb_settings":null,"seo_analyzer_scan_date":null},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.avantea.it\/de\/\" title=\"Home\">Home<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">\u00bb<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.avantea.it\/de\/category\/nicht-kategorisiert\/\" title=\"Nicht kategorisiert\">Nicht kategorisiert<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">\u00bb<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\tOPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding\n\t\t<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Home","link":"https:\/\/www.avantea.it\/de\/"},{"label":"Nicht kategorisiert","link":"https:\/\/www.avantea.it\/de\/category\/nicht-kategorisiert\/"},{"label":"OPU-ICSI: The Biotechnology Revolutionizing Sport Horse Breeding","link":"https:\/\/www.avantea.it\/de\/nicht-kategorisiert\/opu-icsi-the-biotechnology-revolutionizing-sport-horse-breeding\/"}],"_links":{"self":[{"href":"https:\/\/www.avantea.it\/de\/wp-json\/wp\/v2\/posts\/16017","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.avantea.it\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.avantea.it\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.avantea.it\/de\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.avantea.it\/de\/wp-json\/wp\/v2\/comments?post=16017"}],"version-history":[{"count":1,"href":"https:\/\/www.avantea.it\/de\/wp-json\/wp\/v2\/posts\/16017\/revisions"}],"predecessor-version":[{"id":16751,"href":"https:\/\/www.avantea.it\/de\/wp-json\/wp\/v2\/posts\/16017\/revisions\/16751"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.avantea.it\/de\/wp-json\/wp\/v2\/media\/15384"}],"wp:attachment":[{"href":"https:\/\/www.avantea.it\/de\/wp-json\/wp\/v2\/media?parent=16017"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.avantea.it\/de\/wp-json\/wp\/v2\/categories?post=16017"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.avantea.it\/de\/wp-json\/wp\/v2\/tags?post=16017"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}