Animal cloning

Cloning is a procedure by which the cell nucleus (obtained from a skin biopsy of the animal to be cloned) is transferred into an enucleated oocyte, thereby obtaining an individual genetically identical to the cell donor. The molecules present in the oocyte cytoplams can “reprogramme” the cell nucleus that has been inserted in such a way that the cell behaves as an embryonic cell. The embryo obtained can be transferred in the uterus of a recipient female in order to have an identical individual to the cell’s skin donor.

The cloning techinique may be applied for different purposes, among these:

  • for multiplying genetically superior animals;
  • to preserve endangered species;
  • to generate the clone of a castrated male (this is the case of many horses for competitions which are castrated at young age and then became champions) in order to obatin the next generation and to continue the bloodlines that would otherwise be lost;
  • even in the event of sudden death of important animals, the cloning techniques offers the opportunity of obtaining an identical copy as long as the skin biopsy is collected, kept refrigerated and delivered to our lab within a short time.

For further information, contact us.

Cloning of Pieraz

In 2005, Pieraz-Cryozootech-Stallion, the clone of famous Pieraz, was generated by Avantea team. Pieraz as a castrated horse could not pass on its genetic heritage and give rise to a progeny. On the other hand, its clone, Pieraz-Cryozootech owned by Cryozootech S.A is a stallion with high fertility – this demonstrates the normality of an animal obtained by cloning  - already sired many foals,  which in turn have already started their reproductive carrear. In the pictures Pieraz-Cryozootech (A), adult (B – photo by Cryozootech) and Pierazade, filly of Pieraz-Cryozootech already mother of a foal (C – photo by Cryozootech).

Creating copies of animals for breeding

The animal breeding industry could benefit substantially from the cloning of genetically superior animals and the industry of animal genetics could as well clone the best sires for semen production; in fact, our laboratory has gone in this second direction with the production of the bull Galileo, first clone in the world of a progeny tested sire and afterwards with the cloning of Carol Prelude MTOTO ET TV G.M. **TL.